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EPIVIR-HBV® TABLETS AND ORAL SOLUTION (USED TO TREAT CHRONIC HEPATITIS B). Your doctor may want to test you for HIV before you start using Epivir-HBV® and during your treatment. DESCRIPTION EPIVIR (also known as 3TC) is a brand name for lamivudine, a synthetic nucleoside analogue with. Lamivudine-HBV contains a lower dose of the drug lamivudine, which is used to treat HIV infection as well as hepatitis B. Please see the EPIVIR-HBV package insert for information regarding the inhibitory activity of lamivudine against HBV. The most serious side include muscle pain, liver failure, pancreatitis, and liver failure. HIV is the virus that can cause acquired immunodeficiency syndrome (AIDS). Epivir HBV is an antiviral medicine that prevents human immunodeficiency virus ( HIV) or hepatitis B virus from multiplying in your body. Drug interactions, and dosage, and pregnancy and breastfeeding safety information should be reviewed prior to taking this medication synergistic antiretroviral activity. Resistance: Lamivudine-resistant variants of HIV-1 have been selected in cell culture. PATIENTS WITH HIV INFECTION SHOULD RECEIVE ONLY DOSING FORMS APPROPRIATE FOR TREATMENT OF HIV (SEE WARNINGS AND PRECAUTIONS). Epivir is for treating HIV in adults and children at least 3 months old. Contraindications EPIVIR-HBV is contraindicated in patients with a previous hypersensitivity reaction to lamivudine. 1 Exacerbations of Hepatitis after Discontinuation of Treatment. Genotypic analysis showed that the resistance was due to a specific amino acid substitution in. Strength (s): 100MG [ AB] Note: No generic formulation of the following product is available. • EPIVIR-HBV may lower the ability of HBV to multiply and infect new liver cells. If you have hepatitis B but you do not have HIV or AIDS, you can use Epivir-HBV®. Warnings and Precautions Exacerbations of Hepatitis after Discontinuation of Treatment. • EPIVIR-HBV may improve the condition of your liver. [4] [6] Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV/AIDS.. Epivir-HBV oral solution: A clear, colorless to pale yellow, strawberry-banana–flavored liquid, containing 5 mg of lamivudine per 1 mL. The trial compared EPIVIR-HBV 100 mg once daily for 52 weeks, followed by either EPIVIR-HBV 100 mg or matching placebo once daily for 16 weeks (Arm 1), versus placebo once daily for 68 weeks (Arm 2). EPIVIR-HBV oral solution: A clear, colorless to pale yellow, strawberry-banana–flavored liquid, containing 5 mg of lamivudine per 1 mL. Contraindications Epivir-HBV is contraindicated in patients with a previous hypersensitivity reaction to lamivudine. Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue anti-hepatitis B therapy Approval date: January 2, 2014. It is important to take Epivir® as part of a combination regimen.. Use of lamivudine-HBV in patients with unknown or untreated HIV infection could result in new types of HIV virus that are more difficult to treat (drug-resistant) Lamivudine (3tc) (Epivir; Epivir HBV) is a drug prescribed for the treatment of HIV infection and hepatitis B infection. Principal endpoint comparisons for the histologic and serologic outcomes in subjects receiving EPIVIR-HBV (100 mg daily) or placebo in these trials are shown in the following tables EPIVIR-HBV Oral Solution is for oral administration. It is not known if EPIVIR-HBV is safe and. • The long-term benefits of taking EPIVIR-HBV for treatment of chronic hepatitis B infection are not known. If treatment with epivir-hbv is prescribed for chronic hepatitis b for a patient with unrecognized or untreated hiv infection, rapid emergence. Epivir-HBV®Severe acute exacerbations of hepatitis B have been reported in patients who have discontinued anti-hepatitis B therapy (including lamivudine). Your medicine may need to be changed based on these test results. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Epivir-HBV.

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